Metronidazole

Description

Metronidazole is a potent antimicrobial and anti-inflammatory active used in skincare for calming irritated, acne-prone, or rosacea-prone skin. It helps reduce redness, soothe flare-ups, and support a clearer, calmer complexion. Your powder is suitable for cosmetic formulation, not for internal use.

Uses in Skincare (Medicated)
When used in skincare formulations (creams, gels, lotions), metronidazole provides several benefits for certain dermatological conditions:
Rosacea Treatment: It is one of the most common and effective treatments for the redness, pimples, and pustules associated with rosacea, likely due to its anti-inflammatory properties and ability to control Demodex folliculorum mites.
Acne Vulgaris: It can be used in combination therapy for acne to help reduce inflammation and control P. acnes bacteria.
Perioral Dermatitis: It is a common topical treatment for this facial rash.
Wound Healing: It has been shown to reduce odor and inflammation in certain types of chronic or palliative wounds.

INGREDIENT INFORMATION

CAS No: 443-48-1
INCI: Metronidazole
Percentage Purity: 99% 
Colour & Appearance: White to off-white crystalline powder
Recommended Usage Rate: 0.5% – 1% → Mild soothing formulas,
• 1% – 2% → Standard skincare gels, creams, serums
• Up to 5% → High-strength/dermatological (not typically cosmetic)
Soluble: Soluble in water (about 10 mg/mL)
• Slow dissolution → stir well, warm gently
• Not soluble in oils
Stable in pH Range: Works best in pH 5.0 – 7.0
• Avoid very acidic formulations (below pH 4.5)
Formulation Tips:                                                                                                   

• Add to the water phase
• Can be heated up to 50–60°C to help dissolve
• Combine with soothing agents like niacinamide, allantoin, bisabolol
• Works well in gels, creams, lotions, spot treatments

PLEASE NOTE:

Professional Consultation: Before using any product containing metronidazole, you should consult a dermatologist or healthcare provider to ensure it is appropriate for your specific skin condition.

Potential Side Effects: While generally well-tolerated, side effects can include skin irritation, dryness, or a metallic taste if accidentally ingested.

Packaging:

Our powders are packed in waterproof zip-lock pouches to avoid spillage.

Recommended Storage:

Store in a cool, dry place away from direct sunlight and moisture in an airtight container.(Current lot will expire August 2028)

DISCLAIMER:

• For laboratory, research, or professional use only. Should be handled by trained personnel following appropriate protocols.

• This information is not intended to diagnose, treat, cure, or prevent any disease.

• Buyers are responsible for researching, testing, and understanding ingredients before purchasing.

• If you are not trained in handling regulated actives, we strongly recommend working with a chemist or licensed professional.