Metronidazole

Description

Metronidazole is primarily an antibiotic and anti-inflammatory medication used in medicated skincare products to treat specific conditions like rosacea and acne. It is available as a powder for pharmaceutical compounding, but its use in general consumer cosmetics is limited, and such products are typically considered over-the-counter or prescription medications rather than standard cosmetics.

Key Functions & Benefits:

Uses in Skincare (Medicated)
When used in skincare formulations (creams, gels, lotions), metronidazole provides several benefits for certain dermatological conditions:
Rosacea Treatment: It is one of the most common and effective treatments for the redness, pimples, and pustules associated with rosacea, likely due to its anti-inflammatory properties and ability to control Demodex folliculorum mites.
Acne Vulgaris: It can be used in combination therapy for acne to help reduce inflammation and control P. acnes bacteria.
Perioral Dermatitis: It is a common topical treatment for this facial rash.
Wound Healing: It has been shown to reduce odor and inflammation in certain types of chronic or palliative wounds.

INGREDIENT INFORMATION

CAS No: 443-48-1
INCI: Metronidazole                                                                                                                                          Chemical Class: Nitroimidazole derivative                                                                                                Molecular Formula: C₆H₉N₃O₄  
Percentage Purity: 99% 
Colour & Appearance: White to pale yellow crystalline powder                                               Odor: Odorless or faint characteristic odor
Recommended Usage Rate: 0.75% – 1.0% 
Solubility: Freely soluble in: Water (warm), Ethanol, Propylene glycol
Stable in pH Range: 5-7
Mixing Method:                                                                                                                           Cream/Lotion (O/W):
Pre-wet metronidazole with a little water, glycerin, or propylene glycol, then add to the water phase (or mix into finished cream during cool-down).
• Gel:
Pre-wet powder , add into hydrated gel base , mix and adjust pH.

Key notes:
• Always pre-wet/levigate to avoid lumps

Common Uses:
In cosmetic/dermatology formulations, metronidazole is included in:
• Dermatological gels
• Creams
• Anti-inflammatory skin preparations
• Deodorizing/anti-odor formulations

Versatility: Stable under normal conditions
• Protect from:
• Direct sunlight
• Excess heat
• Moisture

Professional Consultation: Before using any product containing metronidazole, you should consult a dermatologist or healthcare provider to ensure it is appropriate for your specific skin condition.
Potential Side Effects: While generally well-tolerated, side effects can include skin irritation, dryness, or a metallic taste if accidentally ingested.

Packaging:

Our powders are packed in waterproof zip-lock pouches to avoid spillage.

Recommended Storage:

Store in a cool, dry place away from direct sunlight and moisture in an airtight container.
(Current lot will expire August 2028)

DISCLAIMER:

• DAKITZ NATURAL PRODUCTS are for cosmetic and personal care formulations and are meant for external use only, unless otherwise stated.

• This information is not intended to diagnose, treat, cure, or prevent any condition.

• Kindly research, test, and understand ingredients before purchasing.

• If you are not advanced in formulating, we recommend working with a chemist or professional formulator.