Description

Angelica polymorpha Sinensis root extract is an herbal extract derived from the root of the plant Angelica Sinensis with possible anti-inflammatory, antispasmodic, vasodilatory, estrogenic, and antitumor activities. Angelica Sinensis contains volatile oils, including safrole, isosafrole, and n-butylphthalide; coumarin derivatives, including psoralens, bergapten, osthol, imperatorin, and oxypeucedanin; and ferulic acid. The coumarin derivatives in this agent may vasodilate and relax smooth muscle and may exhibit additive anticoagulant effects. Ferulic acid, a phenolic phytochemical present in plant cell walls, may neutralize free radicals such as reactive oxygen species. Besides, Angelica Sinensis extract has been shown to inhibit the growth and induce apoptosis of glioblastoma multiform brain tumor cells through p53-dependent and p53-independent pathways.

The Benefits of angelica polymorpha Sinensis root extract

The indications for this herb in TCM are clear, to circulate and nourish the blood. Here we are referring to the system of Blood and not the liquid we commonly think of in our veins. The herb is sweet, acrid, bitter and warm. These are all energetic qualities known to harmonize and invigorate. It is used for convalescence, and feelings of weakness, chilliness, and frailty, especially in Women. The herb alone and in conjunction with other botanicals in the formula provides a natural hormonal balance during the onset of menopause and is good support for the peri-menopause and menopausal years.

The beneficial qualities of Angelica root have been extracted and naturally preserved in a base of certified organic plant glycerin to make this extract. This herb has significant anti-aging properties – scientific testing has established its ability to block collagenase and elastase, the enzymes which cause break down of collagen & elastin. It is also a powerful skin detoxifier assisting with acne, clogged pores and irritations so are particularly suitable for oily skin.

To develop a new whitening agent for cosmetics from natural products, Angelica dahurica was selected for its inhibitory effect on melanogenesis in B16 melanoma cells. From the mechanism study, it was clarified that the ethanolic extracts of this plant showed the suppression of tyrosinase synthesis but no inhibition of tyrosinase activity. To find the active constituents from this plant, the ethanol extracts were chromatographed repeatedly with silica gel. Two coumarin compounds were isolated from A. dahurica. Their structures were identified by physicochemical and spectral data such as UV, IR, NMR, and MS. It was shown that the active substance was isoimperatorin (10-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g][1] benzopyran-7-one) and imperatorin (9-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g][1] benzopyran-7-one). They significantly inhibited tyrosinase synthesis in B16 melanoma cells. To elucidate the action mechanism of the active compounds of A. dahurica, we investigated the changes in the mRNA level of tyrosinase using the RT-PCR technique. As a result, the mRNA level of tyrosinase was markedly reduced by active compounds of A. dahurica. From these results, we suggest that these extracts might be useful as a new whitening agent in cosmetics, but the in vitro findings must be verified in vivo skin-lightening studies.

This product can be used for products targeting Hyperpigmentation, wrinkles, dryness, free radicals damage, sun damage, and fine lines. It can be used to Treats dark under-eye circles, rosacea skincare, varicose veins, and general anti-aging skincare

CAS NUM: 308068-61-3, 299184-76-2

INCI Name: Angelica polymorpha Sinensis root extract

Specification: 1:3

Grade:Cosmetic grade

Recommended Usage: 1-10%

Solubility: Water

Applications: anti-aging products

Country of Origin: Asia

Packaging: Our water/Liquid based ingredients are bottled in plastics avoid spillage.

Recommended Storage: Our water/Liquid based ingredients should be stored in cool temperatures away from direct sunlight and moisture in an airtight container.

PLEASE NOTE: The product image and packaging shown above is a general representation of the product. Product colour may vary from batch to batch and the packing available may be different.
Our products are for external use only unless otherwise indicated. This information is for information purposes and is not intended to diagnose, treat, cure, or prevent any disease.

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– DAKITZ NATURAL PRODUCTS are for cosmetic, personal care formulations and are meant for external use only unless otherwise STATED.

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